The O'Farrell Lab at UCSF
Zhongsheng Yu


    • 2004 - 2008 B.Sc. College of Life Sciences, Jilin University.
    • 2008 - 2014 PhD. Institute of Biophysics, Chinese Academy of Sciences.
    • 2014 - present Postdoc, Department of Biochemistry and Biophysics, UCSF.

Zhongsheng's Publications
  1. Yu, Z.*, Chen, H.*, Liu, J., Zhang, H., Yan, Y., Zhu, N., Guo, Y., Yang, B., Chang, Y., Liang, X. et al. (2014). Various applications of TALEN- and CRISPR/CAS9- mediated homologous recombination to modify the Drosophila genome. Biology Open 0, 1-10 doi: 10. 1242/bio. 20147682
  2. Yu, Z.*, Ren, M.*, Wang, Z., Zhang, B., Rong, Y. S., Jiao, R. and Gao, G. (2013). Highly efficient genome modifications mediated by CRISPR/Cas9 in Drosophila. Genetics. 195: 289-291.
  3. Yu, Z., Wu H., Chen, H., Wang, R., Liang, X., Liu, J., Li, C., Deng, W.-M. and Jiao, R. (2013). CAF-1 promotes Notch signaling through epigenetic control of target gene expression during Drosophila development. Development 140, 3635-3644.
  4. Wei, C., Liu, J., Yu, Z., Zhang, B., Gao, G. and Jiao, R. (2013). TALEN or Cas9 - Rapid, efficient and specific choices for genome modifications. Journal of Genetics and Genomics 40, 281-289. [Review]
  5. Liu, J., Li, C., Yu, Z., Huang, P., Wu, H., Wei, C., Zhu, N., Shen, Y., Chen, Y., Zhang, B. et al. (2012). Efficient and specific modifications of the Drosophila genome by means of an easy TALEN strategy. Journal of Genetics and Genomics 39, 209-215.
  6. Yu, Z. and Jiao, R. (2010). Advances in Drosophila gene targeting and related techniques. Frontier in Biology 5(3): 238-245. [Invited review]
  7. Huang, H., Yu, Z., Zhang, S., Liang, X., Chen, J., Li, C., Ma, J. and Jiao, R. (2010). Drosophila CAF-1 regulates HP1-mediated epigenetic silencing and pericentric heterochromatin stability. Journal of Cell Science 123, 2853-2861.
  8. Chen, Y.*, Dui, W.*, Yu, Z., Li, C., Ma, J. and Jiao, R. (2010). Drosophila RecQ5 is required for efficient SSA repair and suppression of LOH in vivo. Protein & Cell 1, 478-490.
  9. * co-first authors